Olanza 10 Dosage/Direction for Use

Oral: Usual adult dose: Antipsychotic: Initially 5 to 10 mg once a day, with a target dose of 10 mg once a day within several days. Dosage may then be adjusted as needed and tolerated at increments or decrements of 5 mg a day, at intervals of not less than one week.
Note: The risk of orthostatic hypotension and syncope may be minimized by initiating therapy with 5 mg a day. If hypotension occurs, a more gradual titration to the target may be considered.
While individual factors that decrease Olanzapine clearance do not necessitate dosage reduction, patients exhibiting a combination of these factors, such as an elderly female nonsmoker, should begin therapy with an initial dosage of 5 mg a day. Dosage should be increased in these patients if clinically necessary.
Debilitated patients, patients predisposed to hypotensive reactions, and patients who may be more pharmacodynamically sensitive to Olanzapine should begin therapy with an initial dosage of 5 mg a day. Dosage should be increased cautiously in these patients if clinically necessary.
In clinical trials, dosages above 10 mg a day were not shown to be more efficacious than 10 mg a day.
Usual adult prescribing limits: 20 mg a day.
Usual pediatric dose: Antipsychotic: Safety and efficacy in children up to 18 years of age have not been established.
Usual geriatric dose: Antipsychotic: see Usual adult dose.
Usual geriatric prescribing limits: see Usual adult prescribing limits.